Postdoc

Research Associate in Cryopreservation

University: Newcastle University, United Kingdom 
Location: Newcastle upon Tyne, United Kingdom
Closing Date: 14th September 2018 

For informal enquiries please contact Dr. Roman Bauer
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An exciting job opportunity as a Postdoctoral Research Associate is available at Newcastle University, between the Institute of Genetic Medicine (IGM) and the School of Computing (CS). The RA will conduct experimental work in a multidisciplinary team, comprising Dr Roman Bauer (CS), Prof. Majlinda Lako (IGM) and Prof. Evelyne Sernagor (Institute of Neuroscience).

You will work on a project studying the impact of cryopreservation on different kinds of biological tissues. Cryogenic processing protocols will be tested and assessed using a wide range of experimental methods, taking into account anatomy, gene expression and electrical activity. The goal of the project led by Dr Roman Bauer, in collaboration with GE Healthcare and CERN, is to model and improve tissue cryopreservation to yield high-quality post-thaw tissue.

You will hold a PhD in a bioscience discipline and have experience in several experimental techniques, which can be for instance immunohistochemistry, primary cell/tissue culture, qPCR and/or pluripotent stem cell differentiation. Ideally, you will also have experience in at least one electrophysiology method, e.g. in patch clamp or multi-electrode array (MEA) recording.

You will be highly ambitious, have excellent written and spoken English language skills, the ability to present clearly your work, supervise students and collaborate efficiently in a multidisciplinary team. You will have the opportunity to learn new experimental techniques (e.g. organoid growth or MEA recordings from retina), develop leadership skills or quantitative or computational skills if you wish.

The post is funded by the Engineering and Physical Sciences Research Council (EPSRC) and tenable for 32 months on a full-time basis. As part of your application, please provide a CV and covering letter which details your prior experience in experimental work.

Organ Preservation Postdoc 

Job Title: Postdoctoral Fellow
Location: Center for Engineering in Medicine
Massachusetts General Hospital & Harvard Medical School  
Closing date: December 2017

CEM is affiliated with Massachusetts General Hospital & Harvard Medical School & Shriners Hospital and houses 6 senior and ~10 junior PIs along with  a research staff >50; it’s also the home to the BioMems Resource Center . The research in the hospital is funded by NIH, NSF, DOD, Shriners, MGH as well as industry.

 More info on CEM can be found at http://www.massgeneral.org/cem/ and http://cem.sbi.org/web/index.htm

Description: We are looking for a talented Postdoctoral Fellow to contribute to our work on whole organ preservation for the purpose of transplantation.

Description of the project: The field of transplantation is facing a serious donor shortage crisis. The World Health Organization estimates organ transplants are meeting less than 10% of global demand. Of critical importance, the field of transplantation suffers from ineffective bio-preservation and stabilization protocols resulting in a short amount of time - currently hours - which organs can be kept alive ex vivo. This creates an inherent bottleneck in the system: most directly, improvement of current organ preservation practices has the potential to improve organ quality, enabling the use of currently discarded organs, decreasing the incidents of graft failure, and extending the in vivo lifetime of the transplanted organ. Further, longer storage durations would enable HLA typing and global matching programs, therefore improving transplantation outcomes, and reducing the burden of immunosuppressive therapy. Similarly, extending ex vivo organ preservation duration will allow for more complete quality control analyses thereby providing more time for complex clinical decisions, reducing unnecessary waste of quality organs, and alleviating concerns about disease transmission between donor and recipient.

Desired Skills and Experience: We are looking for highly motivated and hardworking Postdoctoral Fellows with diverse backgrounds to join our highly interdisciplinary team. Example tasks include (but are not limited to) operation of machine perfusion equipment, solution formulation, cell culture, microscopy and histology, and molecular assays (e.g. ELISAs, qPCR, etc.). The candidate will be supervised by faculty or senior research staff, will be involved in research projects, and expected to contribute and lead research papers.

Expertise in cryobiology, drug delivery, nanotechnology, or biomaterials are examples of highly desirable skills. Also, experience with perfusion technology, live animal handling, cell culture, and molecular assays are added benefits.  

Contact Person: Applications should be sent to both [email protected] (Dr. Mehmet Toner) and [email protected] (Dr. Korkut UYGUN) with the subject line “Postdoc: Organ preservation”.

Postdoc at Stanford University 

Postdoc position for millimeter-scale cryofluidic systems
Stanford University 
Applications accepted until position is filled. 
 
We are seeking a joint postdoctoral fellow or research engineer to help develop millimeter-scale cryofluidic systems for working with and handling functional biomaterials (i.e., cells, cultures, environmental samples). Ideal candidate should be able to work independently, and also with a diverse team of scientists, engineers, and designers to rapidly prototype and iterate on the design and testing of integrated systems (i.e., build a 'box', test a 'box', debug and repeat). Expertise and prior experience in working with fluids in low temperature systems (e.g., -80C) and interfacing low temperature fluidic systems to other mechanical and electronic systems strongly desired. 
Please contact Sindy Tang (Mechanical Engineering, [email protected]) and Drew Endy (Bioengineering, [email protected]) if available and interested along with 1) your CV, 2) a statement describing why you are interested and qualified for the position, and 3) a list of names and contact information of references.

Postdoc Position for Bull Semen Cryopreservation Optimization

The Benson Cryobiology laboratory at the University of Saskatchewan, in collaboration with SEMEX, Inc in Quebecc, is offering a 2-year postdoctoral fellowship to an applicant interested in using novel interdisciplinary techniques to optimize bull semen cryopreservation. The successful candidate will work towards bull semen cryopreservation media optimization by determining biophysical parameters, cryoprotectant toxicities, and toxicity minimizing agents. Then they will use these components in a novel way to determine optimal cryoprotectant media equilibration protocols leading to successful post thaw recovery. This interdisciplinary project combines basic sperm science with mathematical modeling and optimization in an applied setting with access to large donor, recipient, and data pools.

Qualifications:

  • Candidate must be within 6 months of completing their Ph.D. degree in a discipline related to theriogenology or cryobiology.
  • Candidate must have at least one first author publication in the area of mammalian sperm, preferably in sperm cryopreservation.
  • Knowledge of cryobiological principles and sperm preservation techniques is preferred but not required.
  • Candidate must be comfortable with, but not necessarily expert in, mathematical modeling approaches to biology.
  • Candidate must be willing to travel between two principal locations (Saskatchewan and Quebec).

To apply:
Please send a cover letter describing your research interests, research experience, and career goals, as well as a copy of your CV and contact information for three references to: Dr. James Benson at james.benson[at]usask.ca. 



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