N.Evans

2018 Election Winners 

Congratulations to the Society for Cryobiology 2018 election winners for Governor:

  • Rob Ben (re-elected)
  • Estefania Paredes
  • Gang Zhao 

Rob, Estefania, and Gang will begin their three year term as Governor in January 2019. 

To see what these new Governors have in store for the Society, you can re-read their vision statements here.

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2018 Election


Top: John G. Baust, Rob Ben, Ali Eroglu
Botton: Xiaoming "Shawn" He, Peter Kilbride, Estefania Paredes, Gang Zhao

This year's Society for Cryobiology election will be held October 15-29, 2018.  The election is for three Governor-at-Large positions for a three year term, commencing January 2019 and ending December 2021.

DOWNLOAD CANDIDATE BIOGRAPHIES

Meet the candidates







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SLTB 2018 Meeting Report 

Guest Post by Alasdair Kay, University of York, United Kingdom 

Prague 6-7th September 2018

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New Website Consultation

 The Society for Cryobiology's main website is having a face lift, and we're taking this opportunity to rethink the menu structure and content.

View the proposed changes and have your say. 

PROPOSED NEW MENU STRUCTURE 

Additionally, if you'd like to get involved with content creation, either by contributing to the proposed new pages or through a guest blog/event report or anything else you can think of - let Nicole know! Member contributions for the website and newsletter are strongly encouraged. 





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Pierre Boutron Named CryoFellow

Pierre Boutron has recently been announced as the 2018 Society for Cryobiology Basil J. Luyet CryoFellow.

Pictured Above: Society for Cryobiology President, Dayong Gao, presents Pierre Boutron with the Basil J. Luyet Fellow Medal during the opening ceremony of CRYO2018, held July 10, 2018. 

Dr. Boutron is recognized today as the man who taught us how to understand the amorphous, or non-crystalline, state of solutions of cryoprotective agents, however as early as 1978 he was also the first person to envision achieving vitrification at low cooling rates using high concentrations of cryoprotectants. That was one reason he sought to understand the conditions required to prevent significant quantities of ice from forming during either cooling or warming. It was also the reason he set out to discover novel cryoprotectants that would favor vitrification. 

In his 1978 manuscript 'Stability of the Amorphous State in the System Water-Glycerol-Dimethylsulfoxide' published in Cryobiology lengthy tables show in great detail the amount of ice formed in different solutions at different warming rates and temperatures based on differential scanning calorimetry, or DSC, which Dr. Boutron introduced into the field of cryobiology. He also displayed rigorous proof of the absence of ice by X-ray crystallography, or elucidation of the apparent form of ice when ice did form. This paper also introduced the fundamental concept of the existence of critical cooling and warming rates, without which vitrification can hardly even be correctly discussed today. 

Dr. Boutron was also unique in introducing many new candidate cryoprotective agents into consideration, including some, like levo-2,3-butanediol, that inspired much work on the part of others because of its amazing and previously unknown vitrification tendency. He also characterized, with his collaborators, a large number of cryoprotectant solutions, providing a wealth of information that enabled many comparisons to be made between the stability of the amorphous state across very dissimilar solute systems.

However, his pièce de résistance was his fourth theoretical model of the kinetics of ice formation, published in Cryobiology in 1986. The Boutron equation is a kind of cryobiological “theory of everything” that is capable of predicting not only the effect of cooling rate on the quantity of ice formed, but even the shapes of the resulting DSC peaks, and even the shapes and magnitudes of the DSC peaks seen during devitrification upon warming.

One of the criteria for recognition as a CryoFellow is having scientific offspring who have contributed to our field. Dr. Boutron trained Anne Baudot and Patrick Mehl, both of who went on to make significant and even extraordinary contributions to our knowledge of the stability of the amorphous state.

Finally, the lasting contribution of Pierre’s work is reflected in a great many citations and uses of the tools he created. Pierre’s k4 value, now allows us to specify the cooling rate needed to suppress ice formation to any extent we may require for any solution for which k4 is known or can be inferred. The Boutron equation has also allowed critical cooling rates as high as 108 degrees/min and as low as about 1oC/min to be calculated for very dilute or for very concentrated solutions, respectively. We can now calculate the critical warming rate from the critical cooling rate and  we can now compare the warming rates that permit survival after vitrification to the critical warming rates, which opens up many possibilities for future understanding of injury during rewarming.

Finally, you might say that some of Pierre’s legacy offspring were not exactly scientific, but were actual babies, born as a result of vitrifying them as embryos based on the inspiration provided by his discovery of the extreme stability of the amorphous state of propylene glycol. So Dr. Boutron’s legacy lives on in more ways than one, and it is our great pleasure to recognize him as the newest Fellow of the Society for Cryobiology!

Assemble Plus Marine Funding Call



Assemble Plus has opened its second call for access to infrastructure in Marine labs in Europe. 

Assemble Plus funds acess, travel and living expenses for researchers to carry out experiments using marine organisms or equipment available in the marine stations within its member network.

View the Funding Call, check out the FAQ, and visit the Assemble Plus website to find out more information. 

Research Associate in Cryopreservation

University: Newcastle University, United Kingdom 
Location: Newcastle upon Tyne, United Kingdom
Closing Date: 14th September 2018 

For informal enquiries please contact Dr. Roman Bauer
View the Job Description and Postdoc Advertisement
Apply online now

An exciting job opportunity as a Postdoctoral Research Associate is available at Newcastle University, between the Institute of Genetic Medicine (IGM) and the School of Computing (CS). The RA will conduct experimental work in a multidisciplinary team, comprising Dr Roman Bauer (CS), Prof. Majlinda Lako (IGM) and Prof. Evelyne Sernagor (Institute of Neuroscience).

You will work on a project studying the impact of cryopreservation on different kinds of biological tissues. Cryogenic processing protocols will be tested and assessed using a wide range of experimental methods, taking into account anatomy, gene expression and electrical activity. The goal of the project led by Dr Roman Bauer, in collaboration with GE Healthcare and CERN, is to model and improve tissue cryopreservation to yield high-quality post-thaw tissue.

You will hold a PhD in a bioscience discipline and have experience in several experimental techniques, which can be for instance immunohistochemistry, primary cell/tissue culture, qPCR and/or pluripotent stem cell differentiation. Ideally, you will also have experience in at least one electrophysiology method, e.g. in patch clamp or multi-electrode array (MEA) recording.

You will be highly ambitious, have excellent written and spoken English language skills, the ability to present clearly your work, supervise students and collaborate efficiently in a multidisciplinary team. You will have the opportunity to learn new experimental techniques (e.g. organoid growth or MEA recordings from retina), develop leadership skills or quantitative or computational skills if you wish.

The post is funded by the Engineering and Physical Sciences Research Council (EPSRC) and tenable for 32 months on a full-time basis. As part of your application, please provide a CV and covering letter which details your prior experience in experimental work.

CRYO2018 Report 

CRYO2018, which took place July 10-13 at the Spanish National Research Council (CSIC) in Madrid, Spain, was one of the Society's largest meetings in recent memory, attracting 300 abstract submissions and 250 delegates from 35 countries worldwide.

For full details of the program download the electronic copy of the program book and abstract supplement. You can also view all the photos from CRYO2018

Program
The meeting featured 175 oral presentations and over 100 poster presentations, across 5 plenary sessions, 10 symposia, 17 sessions and 2 poster sessions. Alongside traditional sessions exploring cell and tissue preservation, ice formation, tools and technologies, and plant cryopreservation, there were several sessions which stood out as sessions of note. These included three sessions organized jointly with the Organ Preservation Alliance on the current situation and future research required for organ preservation, and cryopreservation of reproductive tissue for cancer survivors. Additionally, due to the expertise of the local organizing committee, the meeting also included sessions on Cryobiology in Food Science and Technology and Challenges in Cryobiology for Microorganisms. 








 













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Election 2018

Nominations are now open for the 2018 election for 3 governors 2019-2021


The nominations committee is now inviting nominations from all Society members in good standing for the position of Governor 2019-2021. There are 3 posts available. 

Please register your interest in standing for election with Nicole Evans by June 1, 2018. A detailed biography and candidate statement outlining your vision for the Society will be requested thereafter. 

The 2018 nominating committee is: 
Adam Higgins (Chair; President-Elect)
Dayong Gao (President)
Greg Fahy (Governor)
Erik Woods (Governor)
Ido Braslavsky (Governor)

Please note all nominations are subject to approval by the nominations committee. This does not affect your right to nomination by petition as outlined in the society's bylaws

Volunteers Required! 

 

The 2018 tactical plan is ambitious and we need your help to accomplish our goals.

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In Memoriam - Alan P. MacKenzie 

The Society for Cryobiology was saddened to hear of the recent passing of Dr. Alan P. MacKenzie, President of the Society for Cryobiology 1977-1978. Dr. MacKenzie was a lifelong supporter and member of the Society, joining in the Society's founding year - 1964, and continuing his affiliation with the Society throughout his lifetime. 

Alan trained in chemistry at the University of London and enjoyed a long career in freeze-drying from 1959. He published more than 60 papers and a number of book chapters on lyophilization, and lectured and taught the subject in both the US and Europe for more than 25 years. He enjoyed a close relationship with the Center for Pharmaceutical Processing Research (CPPR), acting in a number of capacities during their annual meetings, including as keynote speaker on several occasions. 

During his career Alan held posts at the University of Wisconsin in Madison, and from 1976 - 1990 was based at the University of Washington in the School of Medicine, Faculty of Bioengineering. From 1990 onward he consulted full time for the pharmaceutical and diagnostic industries. 

Alan's research interests included aqueous and other solution chemistries, product formulations, freeze-drying cycle development and validation, process scale-up and technology transfer.

Please send remembrances and condolences to Executive Director, Nicole Evans and she will pass them on to Alan's daughter, Sarah, to share with the family.